How Genetic Is Mental Illness Actually? Heritability Estimates for Mental Health The Role Genes Play

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If one of your family members has a mental illness, does that mean you’re more likely to have it too? Can you inherit a mental illness from a parent? If your mom has, let’s say, social anxiety disorder, and you do too, does that mean that she passed it down genetically or that because she didn’t take you out much, and you watched her being nervous around other people- that you learned to be anxious around other people?

In this video we’re going to talk about heritability estimates- what the research has to tell us about how much genes contribute to mental health. You’ll learn which disorders have the highest rates of heritability and how understanding this can help you make better choices.

So we’re going to jump in to the numbers behind mental health heritability real quick, but first let me clarify a few things. There are no mental health conditions that I know of that are 100% genetic. There is no single gene for any condition, there is not a “depression gene” or “bipolar gene”. Mental health conditions are caused by a whole bunch of complicated interplays between a bunch of genes and our environment and how we think.

The old debate “nature or nurture?” has given way to a much more nuanced exploration of how Nurture- the experiences we have, turn on or turn off various genes (Nature). This is called epigenetics. So research shows that someone who experiences trauma, for example, is much more likely to develop depression or diabetes, because some genes get turned on by those experiences. And even more, those genes that get turned on are more likely to get passed on. So our experiences interplay with our biology in a way that scientists are just beginning to explore.

But, that being said, biological influences do exist and researchers have been able to study this in 2 ways- 1. by comparing twins and 2. researching people that were adopted and raised in a completely different environment than their biological parents. So really smart statisticians and researchers have looked at lots of data and estimated how much genetics contribute to mental illness.

OK, so that being said, let’s look at the numbers: Heritability Estimates
(Check my sources on my blog)

0:00 Introduction
0:50 Clarifications
2:22 Heritability estimates/is mental health inherited?
5:58 Protective factors

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Therapy in a Nutshell and the information provided by Emma McAdam are solely intended for informational and entertainment purposes and are not a substitute for advice, diagnosis, or treatment regarding medical or mental health conditions. Although Emma McAdam is a licensed marriage and family therapist, the views expressed on this site or any related content should not be taken for medical or psychiatric advice. Always consult your physician before making any decisions related to your physical or mental health.
In therapy I use a combination of Acceptance and Commitment Therapy, Systems Theory, positive psychology, and a bio-psycho-social approach to treating mental illness and other challenges we all face in life. The ideas from my videos are frequently adapted from multiple sources. Many of them come from Acceptance and Commitment Therapy, especially the work of Steven Hayes, Jason Luoma, and Russ Harris. The sections on stress and the mind-body connection derive from the work of Stephen Porges (the Polyvagal theory), Peter Levine (Somatic Experiencing) Francine Shapiro (EMDR), and Bessel Van Der Kolk. I also rely heavily on the work of the Arbinger institute for my overall understanding of our ability to choose our life’s direction.
And deeper than all of that, the Gospel of Jesus Christ orients my personal worldview and sense of security, peace, hope, and love https://www.churchofjesuschrist.org/comeuntochrist/believe

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37 Comments

  1. Autism isn't hereditary. I know many autistic children and adults none of whom have autistic parents. I don't know where those studies came from but it sounds like utter hogwash.

  2. Thanks, Emma, for another informative, insightful, and caring video. You mention looking into family history, but that is sometimes a cloudy area, as people in previous generations often didn't discuss or even acknowledge mental and emotional struggles of their own or their relatives. At least that has been my experience. Only though many years of introspection, therapy, and reflection on family behaviors over the years have I realized that it's not 'just me.' Thank you for continuing to lessen the stigma of mental health issues for everyone and their families!

  3. I know that the message at the end is that you can make it better for you children, but I don't think that's always true. I don't think it's always a good decided to have kids if you struggle with mental illness.

    For me, as someone with mental health issues and the majority of my family has even more severe mental illness, having children was a hard no for me. I refuse to saddle a children with the burdens I carry or to pass down the trauma I received from having mentally ill family and loved ones.

    I can't speak for every person with a mental illness, but I do think it's important to validate the decision to not have biological children in the same way we would respect the same decision being made for other diseases with genetic factors, such as cancer. It isn't inherently wrong to have or want kids, but it is something that people should devote a lot of time and thought into before committing to it.

  4. What if what one has to accept is that one will be living with depression for all of one’s life? It can be terrible frustrating to be perpetually told one will get better and to feel one has let family, friends, and doctors down by not getting better.

    And what can those of us who already have a mental illness do with this information about genetics? I thoroughly agree that we all need to work on preventing illnesses through safe homes, good nutrition, etc., but what if that horse has already left the barn?

  5. I remember when as a 14 year old, I was feeling down for about a week. My mom knew I was feeling bad, and took times to talk with and support me. At one point, she said, "Oh, depression runs in the family." I thought, "Oh, great." I did have a hard life as a working adult, but since I retired, I've taken steps to cope with depression. I'd say I'm happier now than I was since leaving childhood.

  6. I’ve been understanding and putting a name to a lot about my limiting beliefs and inner wounds from my childhood. My Mum has residual grief from before I was born and she has general anxiety. She has had numerous breakdowns throughout my childhood that I had to witness. I developed social anxiety that starting in primary school, because of how my Mum would act towards me. This was not in my genes but is how I was raised, in a house with a glass half full attitude and arguments that were too much for my sensitive nature. I developed diabetes at 16, this was because my nervous system took on all that heaviness in the environment. I’m breaking the limiting beliefs for myself and my children, I’ve got a better understanding of what children need to thrive. 💖
    Thank you for your channel, you are a source of information for many.

  7. There is absolutely no way heritability is that high. Just looking at ADHD and anxiety, which have exploded in the last few decades, there's no such thing as a gene that can become expressed so strongly in such a short time. Just like with doctors trying to say myopia is a genetic condition, when it's quite obviously environmental. The same applies to mental illness. When you grow up in a family of anxious people, you pick up that anxiety. When you grow up in a family of highly educated people who developed myopia, you pick up the same indoor, close work habits and develop myopia.

    Someone who explains this really well — and, I would say, the foremost expert on the topic — is Gabor Mate. He makes the link between childhood trauma, and ADHD as a way to distract yourself and cope with the painful experiences, very clear, drawing on his decades of experience as a psychologist helping addicts.

  8. Please understand this is what some scientist say. This is not proven 💯 Emma did mention one could still be happy with proper care of oneself. Just because it runs in your family doesn’t mean one is going to get it. I feel epigentics are awakened or turned on with life experiences, environment etc in some cases not always. That is the point here Not Always. There is hope! Remember our thought process plays a big part. If one thinks there is no hope in curing anxiety etc then there won’t be. I believe there are some mental disorders that are harder to treat like BD or Sch and medication is needed but Dep, anx, and so many others that are treatable. Like Emma mentioned there is a bigger picture. There is still a lot to research and science advances through out the years. Therapy, nutrition, exercise, mental thought and family support are very helpful. Our brains are complex and marvelous that there is still so much to research. Like Emma has mentioned “break the chain”. 🙏

  9. My mom and dad both have anxiety and depression, and it's pretty bad for both of them a lot of the time. Sometimes (a lot maybe) I feel angry at them for having 4 whole children knowing full well how bad their mental health is. All 4 of us are mentally ill in different ways, myself having the worst impact on my life from it as I have agoraphobia, GAD, panic disorder and depression and have been involuntarily hospitalized multiple times, had to drop out of highschool and now I'm on benzos yay lol. Had no significant trauma and I was showing signs as early as pre-k, it's often really heartbreaking for me to have this be the only shot at life I get.

  10. I have found a lot of value in what little of your content I have consumed thus far. This one in particular is interesting and a bit life-affirming.
    I have a child who is 15 months old, but let me tell you a bit about his parents. We were both raised in trauma, which impacted our long-term mental health. My trauma is severe enough that diagnostics cannot currently tell us if I have ADHD or Autism, because those conditions share too many similarities to PTSD and especially severe PTSD. My spouse has severe ADHD in addition to his PTSD. We worried that having a child would be reckless as it is unknown how many factors we can control to reduce their impact on our child. The first step in finding a healthier balance in our approach was to look at the propensity for genetic contribution. It is unlikely that our child will experience the same trauma we did as our circumstances are significantly different and we have both continued to put in work towards recovering from that trauma, but as ADHD is less impacted by environment we knew we would need to be prepared for that.
    At 9 months old our child started to exhibit very clear symptoms of severe ADHD. When we mentioned this to the pediatrician it was dismissed, and we assume that is because they are accustomed to parents guided by emotion rather than research and logic. We don't feel like failures that our child may have ADHD . . . unless we refuse to acknowledge it and thus refuse to accommodate it. So we began researching ADHD friendly living and organizing methods (How To ADHD is a FANTASTIC channel). We went from a child with erratic energy and an insane hyper-focus (if our child is interested in something there is no way to distract away from that interest regardless of how much time has passed, which is a substantial difference from the attention span of most neurotypical toddlers) to a child who was able to move around independently and communicate the stimuli required to function in that moment.
    This is not to say that our child will not later develop some kind of anxiety or other mental illness, but because we know and understand the nature of generational trauma we anticipate integrating mental health care into our child's routine healthcare around the age of 5. This is an exercise in saying "where your parents fail there are healthy options to make up for it."
    Our job as parents is not to protect our children from everything, but to understand where risk needs to be mitigated and teach them how to manage that risk on their own over time. Our ultimate mindset about it is that it is our job to prepare our child for a world where we do not exist. We are older parents and the likelihood our child will lose us earlier than peers the same age lose their parents is significantly greater. So we need to teach adaptive skills and provide reliable resources for long-term success.
    The end. lol

  11. Here is truth. The only thing that truly cures anxiety is Jesus Christ. If you get to know him, and completely trust him, you anxiety will be diminished. He takes away fear from your life. He calls it the "peace that surpasses ALL understanding", including any anxiety medication. "If you declare with your mouth, “Jesus is Lord,” and believe in your heart that God raised him from the dead, you will be saved.". remember that the RAPTURE is going to happen soon, the signs are here.

  12. I understand and appreciate that mental illness heritability is nuanced and lots of factors play a role, but when I look at those in my family with chronic depression (both my grandmothers, one grandfather, my aunt on my father's side, my mother, and now me) it makes me not want to have children.

  13. Why did you presume that just because someone had childhood depression and anxiety means it's genetic. It could be learned helplessness. Psychological and physical violence e.t.c

  14. I started having OCD and depression when i was 8, maybe 9 years old. I didn't have the best childhood, but it definitely wasn't so bad to explain why these terrible disorders developed. There are people who have a childhood 20 times worse than mine who don't develop mental illness. I am convinced that genetics played an essential part in it. As far as i understand, current research strongly implies that epigenetics play a key role. The environment, e.g. being bullied, seems to change the epigenome, which then influences how genes are expressed.

    Epigenetics seem to be the mediator between genes and the environment. That would explain why some people with similar genes get a disorder and some don't. Their environment differs, which changes their epigenome, which changes their gene expression.

    In my opinion we should research gene therapy for psychiatric disorders much more. I know it still sounds like science fiction to many people, but it's becoming more and more realistic. Scientists already used gene therapy to strongly reduce depression in mice and – what's even more interesting – only a few months ago another research team used epigenome editing to reverse changes in mice's epigenome caused by traumatic events. When they did that, the mice's anxiety seemed to return to normal levels. Imagine a world in which no one had to suffer from depression, anxiety disorder etc. I really hope this will become a treatment option in the future.

  15. My dad and I are almost identical personality wise and mental health wise, it’s scary. My little brother was diagnosed with adhd and autism a few years ago, and since then I’ve been researching and have been diagnosed with inattentive adhd, on top of the SAD diagnosis I already had. I’ve been really struggling with my adhd as of late and he’s been helping me through it, and most of the advice he gives is through relatable stories, or because he went through the same thing. He’ll be telling me about something that happened to him or how he used to act in certain situations and I’ll sit there stunned because he just described almost exactly what I’m feeling. Funny thing too, I remember when I first brought up my symptoms when I was looking to get diagnosed, he said, “well if that’s adhd, then I’ve got it too, kid”

    tldr, my dad’s brain got copy and pasted into me

  16. The genetic argument has literally nothing to do with “mental illness”. Utter nonsense. Why don’t you start with the fact that the very descriptions of these “disorders” are scientifically nonsense? Why are you talking crap in the guise of being somewhat expert?
    People like you are why people hoo around believing nonsense about their own minds and the minds of others.
    There’s no definitive test for ANY “mental health disorder”. Once you enter the realms of trying to link them to physical precursors or dispositions then there’s no test of any kind to offer a single indication as to mental health.

  17. Really really great communication about this difficult topic! It's really thought through and biases are left out. Nuances are highlighted ❤ Will use this for some of my classes. Thank you so much.

  18. my grandma had depression and autism, my great grandma had.. no issues as far as I know, but then again I suspect she had depression or some sort of mood disorder, my great grandpa mustve had a problem because he was abusive, maybe war trauma i dunno, my great aunt has a depression disorder, i think two people in my family commited suicide, one is in jail, my great uncle has autism, my father has autism, my grandma on my mom's side had anxiety, my dad's cousin has bipolar, psychosis, severe disorders, and her daughter has autism, my other cousin i think my 2x cousin has a unspecficed anxiety disorder my nephew has autism, my sister has PTSD, my niece has depression disorder and anxiety I also think my dad's cousin also has… maybe like, a anxiety disorder or something, i dunno, I think its a mood disorder because she is my dad's cousin's sister, and then there is me. lol. I have depression disorder, autism, a previous episode of psychosis (i don't have psychosis anymore but i have anxiety about getting psychosis???/anxiety lol) and ocd/anxiety I DONT EVEN KNOW WHERE THE OCD CAME FROM! no one in my family has it! as far as I know of course, how lucky am i?

  19. My girlfriend, her mother, and grandmother all have bad mental illness and it's pretty bad. I'm sure it's genetic…

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