Thomas Insel: Toward a new understanding of mental illness

Today, thanks to better early detection, there are 63% fewer deaths from heart disease than there were just a few decades ago. Thomas Insel, Director of the National Institute of Mental Health, wonders: Could we do the same for depression and schizophrenia? The first step in this new avenue of research, he says, is a crucial reframing: for us to stop thinking about “mental disorders” and start understanding them as “brain disorders.” (Filmed at TEDxCaltech.)

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38 Comments

  1. Before we get too wild with science, why don't we just think of art therapy? Music? Dance? Visual Arts?
    Like that has had profound changes on so many people.

  2. "The polarization of brain medicine into two specialties may in part reflect an intuitive Cartesian dualism in human psychology. Children intuitively accept that certain mental functions, such as perception, planning, or mental calculation, require the brain; however, other functions, such as emotion, desire, belief, or pretense, are independent of the physical organ.

    Related studies have demonstrated that even adults struggle to acquire scientific knowledge that clashes with the innate intuitions of childhood, and tend to revert to intuition for unfamiliar scenarios. Thus, one intriguing possibility is that early failures to identify structural lesions for certain brain disorders, coupled with an innate human reluctance to ascribe certain mental functions to the organ itself, allowed two separate disciplines of brain medicine to emerge.

    This resulted in the current situation: a Cartesian divide between neurology, for disorders of the ‘wires’, and psychiatry, for disorders of the ‘psyche’."

    – Trends in Cognitive Sciences, February 2016

  3. This is the complete opposite approach we need for dealing with mental health. We need a better psychological understanding because most problems are due to childhood trauma. This idea of "brain disorders" is exactly what he says it isn`t, a reductionist approach. He gives very few scientific facts supporting his point.

  4. I know this was posted a long time ago… but I've been saying for years that the way to overcome brain disorders is to start testing and diagnosing children as early as humanly possible. I've been told that it's unethical to diagnose children, and I staunchly disagree. If you diagnose them with something they actually have, like bipolar disorder or schizophrenia or other disorders, it will give them the chance at a normal life. But we don't, we diagnose them with disorders that are allowed to give kids, like Autism and ADHD, giving these kids medication that might actually make their conditions more severe and more catastrophic. We need to learn how to accurately diagnose children, so they don't have to wait until they are 18 or older to start getting a better range of diagnosis options. Limiting a child's diagnosis is limited the possibilities of healthy outcomes.

  5. Did Judy Rappaport really discover the changes occured in the human brains due to schizophrenia or actually rather the damage caused by the drugs used to treat schizophrenia in the brains of these unfortunate people? That's the most important question that awaits a satisfactory answer. If it's the latter rather than the former then needless to say that this creates of an issue of liabilities.

  6. Gotta stop looking at them as diseases but as personality adaptations to external tensors in order to heal them. It's like defining any disease as chronic and then trying to "cure" the patients.

    Let's stop being fools staring at shadows on the wall and start looking at the fire, shall we?

  7. The image he shows of schizophrenic's brains at 10:29 were from people who had been taking antipsychotic drugs. This is much more likely the culprit of the brain volume loss. That's a major miss by Insel in this presentation.

  8. Thomas Insel
    Needs to take Major Tranquilisers
    This is the only way he will ever learn that these drugs shouldn't be used on Humans or Animals
    I have said for over 20 years that I would never want my worst enemy to take Major Tranquilisers
    Because even VERY SHORT TERM USE of these poisons can screw your
    Brain, Body and Nervous System up for life
    If people like Thomas Insel were to screw up their own Bodies, Brains and Nervous Systems
    They would then at least learn what sort of HELP we Patients and Ex Patients really need
    To still have a good life.
    He mentions Suicide
    AKATHISIA Kills
    Withdrawal Symptoms Kill
    Withdrawal Syndromes Kill
    Medication Spellbinding Kills
    Tardive Psychosis Kills
    If Thomas Insel was to try his own 'Medicine' He would know this
    If Thomas Insel was to try his own 'Medicine' He would know what he was talking about.

  9. Unfortunately his talk is based on the premise that brain malfunction simply occurs on its own without any influence from the environment; it's a massive false assumption.

  10. Im sure there is a disorder for every one ! doctors in general have gotten way to liberal with rubber stamping people with a mental illness stamp and prescribing of medicatons . you either wash youre hands too much or too little , either way youre mentaily ill. 🤒

  11. This is merely the second "analysis" of mental illness that I've ever encountered of yours, and overall, I immensely respect your efforts to not only understand but elevate the entire spectrum, from treatment approach and resource accessibility to addressing cultural factors that influence utilization. People like you and undertakings like this are precisely why I was personally drawn to study, with he hopes of one day entering and ultimately transforming (for the better) our healthcare system. I'm just curious about/puzzled by one aspect; it seems you "dance around" specifically acknowledging that mental health is a social disease.

    I have yet to read your book, though I hope to, and I absolutely understand that such claims can carry ramifications, hence your delicate approach (to my knowledge) thusfar. Again, it mostly intrigues me and I'd love/prefer to receive a first-hand elaboration on the subject, rather than be resigned to speculation.

  12. Are all of the statistics stated herein only relevant for the United States of America? Thank you so much for this video! It’s full of Hope for such a sensitive topic that’s often difficult to discuss. My thoughts and prayers are with anyone who suffers from or has been impacted by mental or behavioral disorders.

  13. Neighbor was a PGA golfer. Friends. Never too sure of travel or weather. I agree to mow his lawn. 15 minutes tops. Knocks one day. Not real mad but concerned. On video is me taking a $20 lawn chair out of back yard. Looks just like me. I was mortified down to my toes. Wrote him a check for $50. Apologies accepted, but took the key back to his gate. Went to Dr. MRI of brain. Nothing ! Went to a shrink. Made progress but not on the chair thing. Can’t treat what can’t remember but other issues got better. Stopped after a year.Golfer moved. Two years almost to the day, KNOCK KNOCK. Another video, another chair but they could tell it wasn’t me, besides I was 700 miles away. If he hadn’t driven to my home, I’d never known. I cried. Hugged him for driving all that way.

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